IAPC - IAPC-7 Program

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The preliminary program can be found below. Final program will be published here at the beginning of August.

Monday, August 27

`09:00 – 19:00`	`Course`
`12:00 – 20:00`	`Participant registration (Ritsumeikan University, Osaka-Ibaraki campus, conference hall desk)`
`18:00 – 20:00`	`Welcome dinner (Camping Kitchen)`

Tuesday, August 28

`09:00 – 09:20`	`Opening ceremony`
`PhysChem methods and properties`
`09:20 – 10:00`	`Shinji Yamashita , Setsunan University, Japan` `PhysChem meets ADME`
`10:00 – 10:40`	`Kin Tam, University of Macau, Macau` `Spectrophotometric pKa determination of ionizable pharmaceuticals: Resolution of molecules with weak pH-dependent spectral shift`
`10:40 – 11:00`	`Coffee break & Poster session`
`11:00 – 11:40`	`Alex Avdeef, in-ADME Research,USA` `Capillary Flow Hydrodynamics and Carrier-Mediated Transport of Opioid Derivatives at the BBB: Crone-Renkin-pH and Michaelis-Menten-pH Analyses`
`11:40 – 12:10`	`Godefridus Peters, VU University medical center, The Netherlands Distribution of tyrosine kinase inhibitors in relation to biomimetic properties`
`12:10 – 12:35`	`Exhibitors Presentations`
	`Lunch & Poster session`
`ADME and PK`
`14:00 – 14:40`	`Zoran Mandić, University of Zagreb, Croatia` `Peculiar pharmacokinetics of macrolides. The role of membrane potential`
`14:40 – 15:20`	`Nikoletta Fotaki, University of Bath, UK` `Challenges in Physiologically Based Pharmacokinetic Modeling for the Prediction of In vivo Performance After Oral Administration`
`15:20 – 15:40`	`Coffee break & Poster presentations`
`15:40 – 16:20`	`Masaaki Imono, Shionogi, Japan` `Mechanism analysis of oral absorption enhancement of nanocrystal through dissolution-permeation profile (tentative title)`
`16:20 – 17:00`	`Asami Ono, AsahiKASEI, Japan` `Application of the BCS biowaiver approach to assessing bioequivalence of orally disintegrating tablets with immediate release formulations (tentative title)`
`17:00 – 17:25`	`Guillaume Louit, Sanofi R&D, France` `Prediction of NCE bioavailbility in Dog based on physicochemical profiling, modeling and confirmation in vivo to prepare first in human studies`
`17:25 – 18:00`	`Presentations`
`18:30 – 20:30`	`Conference dinner: Garden Terrace Lion at Ritsumeikan University, Osaka-Ibaraki campus`

Wednesday, August 29

`Solid state session`
`09:00 – 09:40`	`Makoto Mukaida, AsahiKASEI, Japan` `Validation of in silico model for predicting co-crystal formation using co-crystal former exchange reaction (tentative title)`
`09:40 – 10:20`	`Rolf Hilfiker, Solvias, Switzerland` `The challenge to find a new viable solid form – From screening to characterization, selection and scale-up`
`10:20 – 10:40`	`Coffee break & Poster session`
`10:40 – 11:20`	`Katsuhiro Kobayashi, Daiichi-Sankyo Co., Ltd., Japan` `Effective and Convenient Salt & Cocrystal Crystallization Screening Using Water Suspension Method`
`11:20 – 12:00`	`Hideomi Kijima, Ono Pharmaceuticals, Japan` `Contact Secondary Nucleation and Self Assembled Monolayer`
`12:00 – 12:40`	`Daiki Nagamatsu, Shionogi, Japan` `Evaluation of the crystallization difficulty of organic compounds using the critical supersaturation ratio (tentative title)`
	`Lunch & Poster session`
`14:00 – 20:00`	`Excursion to Kyoto Arashiyama`

Thursday, August 30

`Pharma analytical technology session`
`09:00 – 09:40`	`Klara Valko, Bio-mimetic chromatography Ltd, UK` `Application of biomimetic HPLC to estimate in vivo distribution of new modalities (peptides and macrocycles)`
`09:40 – 10:20`	`Konstantin Tsinman, PION, USA` `In Vivo Predictive Dissolution – Flux Measurements`
`10:20 – 10:50`	`Coffee break & Poster session`
`10:50 – 11:30`	`Konstantin Tsinman, USA` `Innovative In Situ Measuring Tools for Formulation Development`
`11:30 – 12:10`	`Alex Avdeef, in-ADME Research, USA` `Ksp of Drug Salts and Cocrystals: Simulations to Improve Design of Experiments According to the Interlaboratory Consensus Recommendations`
`12:10 - 13:30`	`Lunch and Poster presentations`

`Special session: Supersaturating DDS`
`13:30 – 14:10`	`Patrick Augustijns, University of Leuven, Belgium)` `In-vivo gastrointestinal supersaturation in humans`
`14:10 – 14:50`	`Shunsuke Osaki, Eisai,Japan` `Kinetic analysis of crystallization for the prediction of drug supersaturation behavior`
`14:50 – 15:20`	`Coffee break & Poster session`
`15:20 – 16:00`	`Shou-Cang Shen, Institute of Chemical and Engineering Sciences, Singapore` `Mesoporous Excipients for Effective Delivery of Poorly Soluble Drugs`
`15:40 – 16:20`	`Abu Serajuddin, St. John University,USA` `Development of Supersaturating Solid Dispersions of Poorly Water-Soluble Basic Drugs by Interaction with Non-Salt Forming Weak Carboxylic Acids and with HPMC-AS`
`16:20 – 17:00`	`Hikaru Sugihara, Ono Pharmaceuticals,Japan` `Evaluation of Supersaturation Behavior of Pazopanib Hydrochloride in the Presence of HPMC by pH-Shift Dissolution Testing`
`17:00`	`Conference closing`