The preliminary program can be found below. Final program will be published here at the beginning of August.
Monday, August
27
09:00 – 19:00 |
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12:00 – 20:00 |
Participant registration (Ritsumeikan University, Osaka-Ibaraki campus, conference hall desk) |
18:00 – 20:00 |
Welcome dinner (Camping Kitchen) |
Tuesday, August 28
09:00 – 09:20 |
Opening ceremony |
PhysChem methods and properties |
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09:20 – 10:00 |
Shinji Yamashita , Setsunan University, Japan PhysChem meets ADME |
10:00 – 10:40 |
Kin Tam, University of Macau, Macau Spectrophotometric pKa determination of ionizable pharmaceuticals: Resolution of molecules with weak pH-dependent spectral shift |
10:40 – 11:00 |
Coffee break & Poster session |
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Capillary Flow Hydrodynamics and Carrier-Mediated Transport of Opioid Derivatives at the BBB: Crone-Renkin-pH and Michaelis-Menten-pH Analyses |
11:40 – 12:10 |
Godefridus Peters, VU University medical center, The Netherlands |
12:10 – 12:35 |
Exhibitors Presentations |
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Lunch & Poster session |
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14:00 – 14:40 |
Zoran Mandić, University of Zagreb, Croatia Peculiar pharmacokinetics of macrolides. The role of membrane potential |
14:40 – 15:20 |
Nikoletta Fotaki, University of Bath, UK Challenges in Physiologically Based Pharmacokinetic Modeling for the Prediction of In vivo Performance After Oral Administration |
15:20 – 15:40 |
Coffee break & Poster presentations |
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Mechanism analysis of oral absorption enhancement of nanocrystal through dissolution-permeation profile (tentative title) |
16:20 – 17:00 |
Asami Ono, AsahiKASEI, Japan Application of the BCS biowaiver approach to assessing bioequivalence of orally disintegrating tablets with immediate release formulations (tentative title) |
17:00 – 17:25 |
Guillaume Louit, Sanofi R&D, France Prediction of NCE bioavailbility in Dog based on physicochemical profiling, modeling and confirmation in vivo to prepare first in human studies |
17:25 – 18:00 |
Presentations |
18:30 – 20:30 |
Conference dinner: Garden Terrace Lion at Ritsumeikan University, Osaka-Ibaraki campus |
Wednesday, August 29
Solid state session |
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09:00 – 09:40 |
Makoto Mukaida, AsahiKASEI, Japan Validation of in silico model for predicting co-crystal formation using co-crystal former exchange reaction (tentative title) |
09:40 – 10:20 |
Rolf Hilfiker, Solvias, Switzerland The challenge to find a new viable solid form – From screening to characterization, selection and scale-up |
10:20 – 10:40 |
Coffee break & Poster session |
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Effective and Convenient Salt & Cocrystal Crystallization Screening Using Water Suspension Method |
11:20 – 12:00 |
Hideomi Kijima, Ono Pharmaceuticals, Japan Contact Secondary Nucleation and Self Assembled Monolayer |
12:00 – 12:40 |
Daiki Nagamatsu, Shionogi, Japan Evaluation of the crystallization difficulty of organic compounds using the critical supersaturation ratio (tentative title) |
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Lunch & Poster session |
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Thursday, August 30
Pharma analytical technology session |
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09:00 – 09:40 |
Klara Valko, Bio-mimetic chromatography Ltd, UK Application of biomimetic HPLC to estimate in vivo distribution of new modalities (peptides and macrocycles) |
09:40 – 10:20 |
Konstantin Tsinman, PION, USA In Vivo Predictive Dissolution – Flux Measurements |
10:20 – 10:50 |
Coffee break & Poster session |
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Innovative In Situ Measuring Tools for Formulation Development |
11:30 – 12:10 |
Alex Avdeef, in-ADME Research, USA Ksp of Drug Salts and Cocrystals: Simulations to Improve Design of Experiments According to the Interlaboratory Consensus Recommendations |
12:10 - 13:30 |
Lunch and Poster presentations |
Special session: Supersaturating DDS |
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13:30 – 14:10 |
Patrick Augustijns, University of Leuven, Belgium) In-vivo gastrointestinal supersaturation in humans |
14:10 – 14:50 |
Shunsuke Osaki, Eisai,Japan Kinetic analysis of crystallization for the prediction of drug supersaturation behavior |
14:50 – 15:20 |
Coffee break & Poster session |
15:20 – 16:00 |
Shou-Cang Shen, Institute of Chemical and Engineering Sciences, Singapore Mesoporous Excipients for Effective Delivery of Poorly Soluble Drugs |
15:40 – 16:20 |
Abu Serajuddin, St. John University,USA Development of Supersaturating Solid Dispersions of Poorly Water-Soluble Basic Drugs by Interaction with Non-Salt Forming Weak Carboxylic Acids and with HPMC-AS |
16:20 – 17:00 |
Hikaru Sugihara, Ono Pharmaceuticals,Japan Evaluation of Supersaturation Behavior of Pazopanib Hydrochloride in the Presence of HPMC by pH-Shift Dissolution Testing |
17:00 |
Conference closing |